He called it “ Do not scratch that mole!” Niethammer wrote a commentary on the paper, extrapolating what the results might mean for humans. The study found that injuring the fish’s tail fin every couple of weeks for several months greatly increased the rate of cancer formation in that spot. Like humans, zebrafish are prone to getting melanoma, a type of skin cancer. Niethammer’s mind not too long ago when he read a research article describing how repeated injury to the tail fin of a zebrafish could cause tumors to develop. “But I knew it was bad, so I didn’t do it.” “I am not sure I knew what might happen if I scratched,” says the Sloan Kettering Institute cell biologist. Growing up, Philipp Niethammer learned from his mother to never scratch his moles. This is one example of how the environment surrounding an abnormal cell can influence its fate. Scientists are learning that inflammation can play a role in cancer development.
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